| Transactions |
| Date | Player | POS | Transaction |
|---|
| Dec 5, 2018 | A.J. Green | WR | on IR, toe |
| Nov 29, 2018 | Andre Smith | | signed |
| Nov 29, 2018 | Jake Fisher | T | on IR, back |
| Nov 26, 2018 | Andy Dalton | QB | on IR, right thumb |
| Nov 26, 2018 | Tom Savage | QB | acquired from waiver |
| Nov 23, 2018 | Adolphus Washington | DT | on IR, knee |
| Nov 23, 2018 | Christian Ringo | | active/prac. squad |
| Nov 22, 2018 | Josh Tupou | DT | on IR, pectoral |
| Nov 22, 2018 | Niles Scott | NT | active/prac. squad |
| Nov 20, 2018 | Aaron Wallace | LB | pract. squad add |
| Nov 20, 2018 | Andrew Brown | DT | pract. squad del |
| Nov 20, 2018 | Hunter Sharp | WR | pract. squad add |
| Nov 20, 2018 | Kasim Edebali | DE | signed |
| Nov 20, 2018 | Preston Brown | MLB | on IR, knee |
| Nov 16, 2018 | Brandon Bell | LB | active/prac. squad |
| Nov 16, 2018 | Tyler Kroft | TE | on IR, foot |
| Nov 5, 2018 | Andrew Vollert | TE | pract. squad add |
| Nov 5, 2018 | Auden Tate | WR | active/prac. squad |
| Nov 5, 2018 | Carl Lawson | DE | on IR, knee |
| Nov 5, 2018 | Christian Hackenberg | QB | pract. squad del |
| Nov 5, 2018 | Clark Harris | LS | re-signed, Two-year extension (through 2020) |
| Nov 5, 2018 | Connor Cook | QB | pract. squad add |
| Oct 23, 2018 | Brandon Bell | LB | pract. squad add |
| Oct 23, 2018 | Jordan Franks | TE | active/prac. squad |
| Oct 23, 2018 | Mason Schreck | TE | on IR, left leg |
| Oct 19, 2018 | Auden Tate | WR | pract. squad add |
| Oct 18, 2018 | Auden Tate | WR | cut |
| Oct 18, 2018 | KeiVarae Russell | CB | active/prac. squad |
| Oct 10, 2018 | Demetrious Cox | | pract. squad add |
| Oct 10, 2018 | Matt Lengel | TE | active/prac. squad |
| Oct 9, 2018 | Thomas Rawls | RB | cut |
| Oct 5, 2018 | Tyler Eifert | TE | on IR, broken right ankle |
| Oct 1, 2018 | Vontaze Burfict | OLB | suspension lifted |
| Sep 28, 2018 | Tra Carson | RB | cut |
| Sep 28, 2018 | Tra Carson | RB | off IR, hamstring |
| Sep 26, 2018 | Adolphus Washington | DT | active/prac. squad |
| Sep 26, 2018 | Ryan Glasgow | DT | on IR, torn ACL |
| Sep 19, 2018 | Thomas Rawls | RB | signed |
| Sep 18, 2018 | Randy Bullock | K | re-signed, Two-year extension (through 2020) |
| Sep 12, 2018 | Matt Barkley | QB | cut |
| Sep 12, 2018 | Matt Barkley | QB | off IR, knee |
| Sep 8, 2018 | Alex Erickson | WR | re-signed, Two-year extension (through 2020) |
| Sep 6, 2018 | Chris Okoye | DT | cut |
| Sep 6, 2018 | Chris Okoye | DT | off IR, undisclosed |
| Sep 6, 2018 | Josh Shaw | CB | cut |
| Sep 6, 2018 | Josh Shaw | CB | off IR, undisclosed |
| Sep 3, 2018 | Christian Hackenberg | QB | pract. squad add |
| Sep 3, 2018 | Michael Johnson | DE | signed |
| Sep 2, 2018 | Andrew Brown | DT | pract. squad add |
| Sep 2, 2018 | Brad Lundblade | OL | pract. squad add |
| Sep 2, 2018 | C.J. Goodwin | DB | pract. squad add |
| Sep 2, 2018 | Chris Worley | LB | pract. squad add |
| Sep 2, 2018 | Jordan Franks | TE | pract. squad add |
| Sep 2, 2018 | KeiVarae Russell | CB | pract. squad add |
| Sep 2, 2018 | Kent Perkins | T | pract. squad add |
| Sep 2, 2018 | Kermit Whitfield | WR | pract. squad add |
| Sep 2, 2018 | Moritz Boehringer | TE | pract. squad add |
| Sep 2, 2018 | Quinton Flowers | RB | pract. squad add |
| Sep 1, 2018 | Andrew Brown | DT | cut |
| Sep 1, 2018 | Brad Lundblade | OL | cut |
| Sep 1, 2018 | Brandon Bell | LB | cut |
| Sep 1, 2018 | Brian Hill | RB | cut |
| Sep 1, 2018 | C.J. Goodwin | DB | cut |
| Sep 1, 2018 | Cethan Carter | FB | on IR, shoulder |
| Sep 1, 2018 | Chris Worley | LB | cut |
| Sep 1, 2018 | Devonte Boyd | WR | cut |
| Sep 1, 2018 | Eddy Wilson | DT | cut |
| Sep 1, 2018 | Jared Murphy | WR | cut |
| Sep 1, 2018 | Jonathan Brown | LB | cut |
| Sep 1, 2018 | Jordan Franks | TE | cut |
| Sep 1, 2018 | Junior Joseph | LB | cut |
| Sep 1, 2018 | Justin Murray | T | cut |
| Sep 1, 2018 | Ka'Raun White | WR | cut |
| Sep 1, 2018 | Kayaune Ross | WR | cut |
| Sep 1, 2018 | KeiVarae Russell | CB | cut |
| Sep 1, 2018 | Kent Perkins | T | cut |
| Sep 1, 2018 | Kermit Whitfield | WR | cut |
| Sep 1, 2018 | Logan Woodside | QB | cut |
| Sep 1, 2018 | Michael Johnson | DE | cut |
| Sep 1, 2018 | Moritz Boehringer | TE | cut |
| Sep 1, 2018 | Quinton Flowers | RB | cut |
| Sep 1, 2018 | Ryan Hewitt | TE | cut |
| Sep 1, 2018 | Simeyon Robinson | DL | cut |
| Sep 1, 2018 | T.J. Johnson | C | cut |
| Sep 1, 2018 | Trayvon Henderson | DB | on IR, knee |
| Sep 1, 2018 | Tyrice Beverette | DB | cut |
| Aug 31, 2018 | Jarveon Williams | RB | cut |
| Aug 30, 2018 | Darius Hillary | CB | cut |
| Aug 28, 2018 | Carlos Dunlap | DE | re-signed, Three-year extension (through 2021) |
| Aug 28, 2018 | Cory Helms | G | cut |
| Aug 28, 2018 | Darius Hillary | CB | signed |
| Aug 28, 2018 | Geno Atkins | DT | re-signed, Four-year extension (through 2022) |
| Aug 24, 2018 | Chris Baker | DT | cut |
| Aug 23, 2018 | Sojourn Shelton | CB | cut |
| Aug 19, 2018 | George Iloka | SS | cut |
| Aug 13, 2018 | Simeyon Robinson | DL | signed |
| Aug 10, 2018 | Austin Fleer | T | cut |
| Aug 10, 2018 | Ray Lawry | RB | cut |
| Aug 4, 2018 | C.J. Goodwin | DB | signed |
| Aug 4, 2018 | Cory Helms | G | signed |
| Aug 4, 2018 | Eddy Wilson | DT | acquired from waiver |
| Aug 4, 2018 | Kayaune Ross | WR | signed |
| Aug 4, 2018 | Rod Taylor | G | on IR, knee |
| Aug 2, 2018 | Brandon LaFell | WR | cut |
| Aug 2, 2018 | Ja'Von Rolland-Jones | DE | cut |
| July 26, 2018 | Jared Murphy | WR | signed |
| July 26, 2018 | Javarius Leamon | T | reserve/DNR |
| July 17, 2018 | Gaelin Elmore | DE | retired |
| June 21, 2018 | Malik Jefferson | LB | signed/draft choice, Four-year contract (through 2021) |
| June 21, 2018 | Sam Hubbard | DE | signed/draft choice, Four-year contract (through 2021) |
